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RS 67333 hydrochloride

CAS No. 168986-60-5

RS 67333 hydrochloride ( RS 67333 HCl; RS 67333 (hydrochloride) )

产品货号. M27698 CAS No. 168986-60-5

potent and highly selective 5-HT4 partial agonist.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥583 有现货
10MG ¥988 有现货
25MG ¥2333 有现货
50MG ¥3661 有现货
100MG ¥5387 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    RS 67333 hydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    potent and highly selective 5-HT4 partial agonist.
  • 产品描述
    potent and highly selective 5-HT4 partial agonist.(In Vitro):RS 67333 hydrochloride exhibits affinities for the sigma 1 (pKi = 8.9) and sigma 2 (pKi = 8.0) binding sites. At the 5-HT4 receptor mediating relaxation of the carbachol-precontracted oesophagus, RS 67333 hydrochloride acts as a potent (pEC50 of 8.4), partial agonists (intrinsic activities, with respect to 5-HT is 0.5) with respect to 5-HT .
  • 同义词
    RS 67333 HCl; RS 67333 (hydrochloride)
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    c-Fgr;Lyn;Hck;Apoptosis
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    168986-60-5
  • 分子量
    389.4
  • 分子式
    C19H30Cl2N2O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Cl.CCCCN1CCC(CCC(=O)c2cc(Cl)c(N)cc2OC)CC1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Weir MC, et al. Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo. ACS Chem Biol. 2018 Jun 15;13(6):1551-1559.
产品手册
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